JAK-IN-24 - CAS 2042629-43-4

JAK-IN-24, a JAK inhibitor, exhibits IC50 values of 0.534 nM and 24 nM in the presence of 4 μM and 1 mM ATP, respectively. Additionally, it effectively inhibits STAT5 phosphorylation induced by PBMC IL-15 with an IC50 of 86.171 nM.

JAK, Others

Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, Stem Cells, Others, Angiogenesis, JAK/STAT signaling

2042582

C20H25N5O2

367.44

N(C1=C2C(NC=C2CCOCC#C)=NC=N1)[C@H]3CN(C(C=C)=O)[C@@H](C)CC3

-20°C

Ice Packs

Small Compound