JAK-IN-25 - CAS 2127110-22-7

JAK-IN-25 (compound 19), a potent JAK inhibitor, exhibits IC50 values of 6 nM for TYK2, 21 nM for JAK1, 8 nM for JAK2, and 1051 nM for JAK3. It also demonstrates an IC50 of 28 nM against human whole blood IL-12 (HEB IL-12) and holds potential for cancer research [1].

JAK

JAK/STAT signaling, Angiogenesis, Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, Stem Cells

2127081

C19H17N5O4

379.37

O=C(OC)C1=NN2C=C(NC(=O)C2=C1)C=3C=NN(C3)CC4=CC=C(OC)C=C4

-20°C

Ice Packs

Small Compound