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JAK-IN-26 - CAS 2417134-93-9

JAK-IN-26 - CAS 2417134-93-9

MF-0156608-01

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Product Details

  • Bioactivity

    JAK-IN-26 (compound 2) is an orally active Janus kinase (JAK) inhibitor with favorable pharmacokinetic properties, demonstrating potency in suppressing IFN-α2B-induced STAT3 phosphorylation in Jurkat cells, with an IC50 value of 17.2 nM [1].

  • Target

    JAK

  • Related Pathways

    Tyrosine Kinase/Adaptors, Stem Cells, JAK/STAT signaling, Chromatin/Epigenetic, Angiogenesis

  • CAS Number

    2417032

  • Molecular Formula

    C22H24N6O3

  • Molecular Weight

    420.46

  • SMILES

    O=C(NC1=NC=C(C(=O)CC)C(=C1)NC2=CC=CC(C=3N=CN(N3)C)=C2OC)C4CC4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound