JAK-IN-31 - CAS 2597016-88-9

JAK-IN-31 (Example 75), a JAK inhibitor, demonstrates IC50 values of ≤0.01 μM for JAK1, ≤0.01 μM for JAK2, 0.01-0.1 μM for JAK3, and ≤0.01 μM for Tyk2, indicating potent activity across these targets. It is utilized in cancer research [1].

JAK

Chromatin/Epigenetic, Angiogenesis, Tyrosine Kinase/Adaptors, Stem Cells, JAK/STAT signaling

2596919

C21H19N7O2S2

465.55

N(C=1C(=CN=C2C1C=CN2)C=3SC(C)=NN3)[C@@H]4C[C@H](NS(=O)(=O)C5=CC(C#N)=CC=C5)C4

-20°C

Ice Packs

Small Compound