JAK kinase-IN-1 - CAS 2698389-43-2

JAK kinase-IN-1 (Example 1) is a potent inhibitor targeting the JAK family, including TYK2, JAK1, JAK2, and JAK3, with IC50 values of 4.2 nM, 32 nM, 27 nM, and 3473 nM, respectively [1].

JAK

Chromatin/Epigenetic, Angiogenesis, JAK/STAT signaling, Stem Cells, Tyrosine Kinase/Adaptors

2698344

C17H19F2N7OS

407.44

C(=O)(N1C2(CN(CC1(SC2)[H])C3=NC(NC=4C=NN(C)C4)=NC=C3)[H])[C@H]5C(F)(F)C5

-20°C

Ice Packs

Small Compound