JAK1-IN-12 - CAS 2945204-95-3

JAK1-IN-12, a selective inhibitor of JAK1, exhibits an IC50 of 0.0246 μM and demonstrates IC50 values of 0.423 μM, 0.410 μM, and 1.12 μM for JAK2, JAK3, and TYK2, respectively. It promotes hair growth in mice and is applicable for researching immune and inflammatory diseases [1].

JAK

Tyrosine Kinase/Adaptors, Stem Cells, Chromatin/Epigenetic, JAK/STAT signaling, Angiogenesis

2945204-95-3

C20H23N5O

349.43

N([C@@H]1[C@@]2(CC3(O)C[C@@]1(CC(C2)C3)[H])[H])C=4C(=CN=C5C4C=CN5)C=6C=NNC6

-20°C

Ice Packs

Small Compound