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Molfinity

JAK1-IN-13 - CAS 2778330-90-6

JAK1-IN-13 - CAS 2778330-90-6

MF-0120819-01

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Product Details

  • Bioactivity

    JAK1-IN-13 (compound 36b) functions as an orally active, potent, and highly selective JAK1 inhibitor, exhibiting an IC 50 of 0.044 nM. It effectively reduces STAT3 phosphorylation [1].

  • Target

    JAK

  • Related Pathways

    Angiogenesis, Stem Cells, JAK/STAT signaling, Tyrosine Kinase/Adaptors, Chromatin/Epigenetic

  • CAS Number

    2778330-90-6

  • Molecular Formula

    C23H26F3N5O

  • Molecular Weight

    445.48

  • SMILES

    N(C1=C2C(=NC=C1C(NC)=O)NC=C2)[C@@H]3C[C@H](C)N(CC4=CC=C(C(F)(F)F)C=C4)CC3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound