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JAK2/FLT3-IN-3 - CAS 3038183-53-5

JAK2/FLT3-IN-3 - CAS 3038183-53-5

MF-0122364-01

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Product Details

  • Bioactivity

    JAK2/FLT3-IN-3 (11r) is a dual inhibitor of FLT3 and JAK2, with IC50 values respectively at 0.51 nM for FLT3, 2.01 nM for JAK2, and 104.40 nM for JAK3. It can induce apoptosis and exhibits anticancer activity.

  • CAS Number

    3038183-53-5

  • Molecular Formula

    C34H45N9O2

  • Molecular Weight

    611.78

  • SMILES

    O=C(NC1=CC=C(C=C1)C(=O)C)N2CCN(C3=NC(=NC=C3C)NC4=CC=C(C=C4)N5CCC(N6CCN(C)CC6)CC5)CC2

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound