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Molfinity

JAK2-IN-10 - CAS 3035735-18-0

JAK2-IN-10 - CAS 3035735-18-0

MF-0148039-01

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Product Details

  • Bioactivity

    JAK2-IN-10 (compound 5) is a potent inhibitor of JAK2v617f, with an IC50 value of ≤10 nM.

  • Target

    JAK

  • Related Pathways

    Tyrosine Kinase/Adaptors, JAK/STAT signaling, Chromatin/Epigenetic, Stem Cells, Angiogenesis

  • CAS Number

    3035735-18-0

  • Molecular Formula

    C33H33D3FN9O2

  • Molecular Weight

    612.71

  • SMILES

    O=C1N(C2=C3C(=C(N=C3NC=C2N1C)C4=CN(CC)N=C4F)C=5C=C6C(=CC5)N(C([2H])([2H])[2H])N=C6)[C@H]7CC[C@](NC(=O)C8CC8)(C)CC7

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Isotope products