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JAK3/BTK-IN-6 - CAS 2243136-03-8
JAK3/BTK-IN-6 - CAS 2243136-03-8
SKU:MF-0139053-01
Regular price
$1,383.80 USD
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$1,383.80 USD
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Product Details
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Bioactivity
JAK3/BTK-IN-6 is a potent dual inhibitor of BTK (IC50: 0.6 nM) and JAK3 (IC50: 0.4 nM) .JAK3/BTK-IN-6 exhibits good metabolic stability in human liver microsomes.JAK3/BTK-IN-6 can be used to study blood and immune diseases.
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Target
Others, BTK, JAK
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Related Pathways
Tyrosine Kinase/Adaptors, JAK/STAT signaling, Angiogenesis, Chromatin/Epigenetic, Others, Stem Cells
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CAS Number
2243136-03-8
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Molecular Formula
C21H17BF3N5O3
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Molecular Weight
455.2
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SMILES
N(C=1C(C(F)(F)F)=CN=C(NC=2C=C3C(=CC2)B(O)OC3)N1)C4=CC(NC(C=C)=O)=CC=C4
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound