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Molfinity

JAK3/BTK-IN-6 - CAS 2243136-03-8

JAK3/BTK-IN-6 - CAS 2243136-03-8

SKU:MF-0139053-01

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  • Bioactivity

    JAK3/BTK-IN-6 is a potent dual inhibitor of BTK (IC50: 0.6 nM) and JAK3 (IC50: 0.4 nM) .JAK3/BTK-IN-6 exhibits good metabolic stability in human liver microsomes.JAK3/BTK-IN-6 can be used to study blood and immune diseases.

  • Target

    Others, BTK, JAK

  • Related Pathways

    Tyrosine Kinase/Adaptors, JAK/STAT signaling, Angiogenesis, Chromatin/Epigenetic, Others, Stem Cells

  • CAS Number

    2243136-03-8

  • Molecular Formula

    C21H17BF3N5O3

  • Molecular Weight

    455.2

  • SMILES

    N(C=1C(C(F)(F)F)=CN=C(NC=2C=C3C(=CC2)B(O)OC3)N1)C4=CC(NC(C=C)=O)=CC=C4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound