JAK3/BTK-IN-7 - CAS 2844387-16-0

JAK3/BTK-IN-7 (XL-12), characterized as a JAK3/BTK inhibitor, exhibits IC 50 values of 2 nM and 14 nM for JAK3 and BTK respectively. This compound demonstrates anti-inflammatory properties and is applicable in research related to rheumatoid arthritis [1].

JAK, BTK

Chromatin/Epigenetic, Tyrosine Kinase/Adaptors, Angiogenesis, Stem Cells, JAK/STAT signaling

2844387-16-0

C29H30N8O4

554.6

NC1=C2C(=NN(C2=NC=N1)[C@H]3CN(C(C=C)=O)CCC3)C4=C5C(=C(NC(=O)C6=CC=C(N(C)C)C=C6)C=C4)OCO5

-20°C

Ice Packs

Small Compound