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JAK3-IN-14 - CAS 454234-24-3
JAK3-IN-14 - CAS 454234-24-3
SKU:MF-0095171-01
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$207.07 USD
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$207.07 USD
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Product Details
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Bioactivity
JAK3-IN-14 is a potent, selective and orally active FLT3 inhibitor, with IC50s of ∼40, 8, and 4 nM for FLT3-WT, FLT3-D835Y, and FLT3-D835H, respectively.
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Target
JAK, FLT
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Related Pathways
JAK/STAT signaling, Stem Cells, Angiogenesis, Tyrosine Kinase/Adaptors, Chromatin/Epigenetic
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CAS Number
454207
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Purity
0.9898
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Molecular Formula
C18H13N3O
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Molecular Weight
287.32
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SMILES
C(=C1C=2C(NC1=O)=CC=C(C2)C=3C=CC=NC3)C4=CC=CN4
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound