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Molfinity

JAK3-IN-14 - CAS 454234-24-3

JAK3-IN-14 - CAS 454234-24-3

SKU:MF-0095171-01

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  • Bioactivity

    JAK3-IN-14 is a potent, selective and orally active FLT3 inhibitor, with IC50s of ∼40, 8, and 4 nM for FLT3-WT, FLT3-D835Y, and FLT3-D835H, respectively.

  • Target

    JAK, FLT

  • Related Pathways

    JAK/STAT signaling, Stem Cells, Angiogenesis, Tyrosine Kinase/Adaptors, Chromatin/Epigenetic

  • CAS Number

    454207

  • Purity

    0.9898

  • Molecular Formula

    C18H13N3O

  • Molecular Weight

    287.32

  • SMILES

    C(=C1C=2C(NC1=O)=CC=C(C2)C=3C=CC=NC3)C4=CC=CN4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound