JAK3-IN-9 - CAS 1430095-30-9

JAK3-IN-9 is a potent and orally active inhibitor of the Janus kinase 3 (JAK3) enzyme, displaying an impressive IC50 value of 1.7 nM. It exhibits high selectivity towards the JAK3 signaling pathway, making it a valuable tool for studying autoimmune diseases. Additionally, JAK3-IN-9 possesses desirable characteristics such as low toxicity and excellent oral bioavailability. It also demonstrates promising anti-arthritis activity, thus enhancing its potential as a therapeutic agent [1].

Others, JAK

Tyrosine Kinase/Adaptors, Others, Chromatin/Epigenetic, JAK/STAT signaling, Angiogenesis, Stem Cells

1430056

C17H23N5O4S

393.46

N([C@@H](C(C)C)C)C=1C(C(N)=O)=CN=C(NC2=CC=C(OS(C)(=O)=O)C=C2)N1

-20°C

Ice Packs

Small Compound