JAK3i - CAS 1918238-72-8

JAK3i is a selective covalent inhibitor of JAK3 kinase. JAK3i reveals two distinct temporal waves of STAT5 phosphorylation and more potently targets the second wave, which is required for cell cycle progression and T cell proliferation.

JAK

Chromatin/Epigenetic, JAK/STAT signaling, Stem Cells, Tyrosine Kinase/Adaptors, Angiogenesis

1918158

>99.99%

C18H15FN4O3

354.34

C(OCC)(=O)C=1C2=C(N=CN=C2NC1)C3=CC(NC(C=C)=O)=CC=C3F

-20°C

Ice Packs

Small Compound