Jaspamycin - CAS 22242-96-2

Jaspamycin (7-CN-7-C-Ino) does not bind with purified human PKARIα but exhibits anti-parasite activity and is a potent activator of PKA, binding to the R site (PKAR) with an EC50 of 6.5 nM and a Kd of 8 nM in Trypanosoma brucei.

Parasite, JAK, PKA

Stem Cells, JAK/STAT signaling, Microbiology/Virology, Angiogenesis, Tyrosine Kinase/Adaptors, Chromatin/Epigenetic

22144

C12H12N4O5

292.25

OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cc(C#N)c2c1nc[nH]c2=O

-20°C

Ice Packs

Small Compound