Jasplakinolide - CAS 102396-24-7

Jasplakinolide (Jaspamide), a naturally occurring cyclic peptide from marine sponges, is a potent inducer of actin polymerization.Jasplakinolide exhibits antifungal and antitumor activity and stabilizes pre-existing actin filaments. Jasplakinolide competitively binds to F-actin with the ghost pen cyclic peptide and has a Kd value of 15 nM for F-actin.

Antifungal, Arp2/3 Complex, Microtubule Associated

Microbiology/Virology, Cytoskeletal Signaling

102365

C36H45BrN4O6

709.67

C(C=1C=2C(NC1Br)=CC=CC2)[C@@H]3C(=O)N[C@H](CC(=O)O[C@@H](C)C[C@@H](C)\C=C(\C)/C[C@H](C)C(=O)N[C@@H](C)C(=O)N3C)C4=CC=C(O)C=C4

-20°C

Ice Packs

Natural Product