Jatrophane 2 - CAS 210108-86-4

2,5,7,8,9,14-Hexaacetoxy-3-benzoyloxy-15-hydroxyjatropha-6 (17),11E-diene (Jatrophane 2) exhibits significant antifeedant activity against a generalist plant-feeding insect, the cotton bollworm (Helicoverpa armigera) . Jatrophane 2 also demonstrates the most powerful inhibition of P-gp, higher than R (+) -verapamil and tariquidar in colorectal multi-drug resistant (MDR) cells (DLD1-TxR) .

Antifection, P-gp

Microbiology/Virology, Neuroscience, Membrane transporter/Ion channel

210018

C39H50O15

758.814

[H][C@]12[C@@H](OC(=O)c3ccccc3)[C@@](C)(C[C@]1(O)[C@@H](OC(C)=O)[C@@H](C)\C=C\C(C)(C)[C@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)C(=C)[C@@H]2OC(C)=O)OC(C)=O |t:26|

-20°C

Ice Packs

Natural Product