JB-95 - CAS 1873323-60-4

JB-95 is a β-hairpin macrocyclic peptide that exhibits potent antibacterial activity against Escherichia coli. It selectively disrupts the outer membrane of E. coli without affecting the inner membrane.

Antibacterial

Microbiology/Virology

1873323-60-4

C92H151N35O14

1971.41

C(C=1C=2C(NC1)=CC=CC2)[C@@H]3NC(=O)[C@]4(N(C(=O)[C@@]5(N(C(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC=6C=7C(NC6)=CC=CC7)NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@]([C@H](CC)C)(NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@]([C@H](CC)C)(NC(=O)[C@H](CCCNC(=N)N)NC3=O)[H])[H])CCC5)[H])CCC4)[H]

-20°C

Ice Packs

Peptide