JBI-589 - CAS 2308504-22-3

JBI-589 is an isoform-selective, non-covalent inhibitor of PAD4 that diminishes CXCR2 expression and impedes neutrophil chemotaxis. Additionally, it attenuates primary tumor growth and metastases, augmenting the efficacy of checkpoint inhibitors [1].

Others, PAD

Chromatin/Epigenetic, Others

2308479

C29H28FN5O

481.56

C(N1C(=CC=2C1=CC=CC2)C3=C(C)N4C(=N3)C=C(C(=O)N5C[C@H](N)CCC5)C=C4)C6=CC=C(F)C=C6

-20°C

Ice Packs

Small Compound