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JBJ-02-112-05 - CAS 2748162-29-8
JBJ-02-112-05 - CAS 2748162-29-8
SKU:MF-0022663-01
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$1,383.80 USD
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$1,383.80 USD
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Product Details
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Bioactivity
JBJ-02-112-05 is a potent, mutant-selective, allosteric, and orally active inhibitor of EGFR, with an IC50 of 15 nM for EGFR L858R/T790M [1].
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Target
EGFR, JAK
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Related Pathways
JAK/STAT signaling, Tyrosine Kinase/Adaptors, Stem Cells, Chromatin/Epigenetic, Angiogenesis
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CAS Number
2748125
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Molecular Formula
C27H20N4O2S
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Molecular Weight
464.54
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SMILES
C(C(NC1=NC=CS1)=O)(N2C(=O)C=3C(C2)=CC=C(C3)C=4C=C5C(=CC4)NC=C5)C6=CC=CC=C6
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound