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Molfinity

JBJ-02-112-05 - CAS 2748162-29-8

JBJ-02-112-05 - CAS 2748162-29-8

SKU:MF-0022663-01

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  • Bioactivity

    JBJ-02-112-05 is a potent, mutant-selective, allosteric, and orally active inhibitor of EGFR, with an IC50 of 15 nM for EGFR L858R/T790M [1].

  • Target

    EGFR, JAK

  • Related Pathways

    JAK/STAT signaling, Tyrosine Kinase/Adaptors, Stem Cells, Chromatin/Epigenetic, Angiogenesis

  • CAS Number

    2748125

  • Molecular Formula

    C27H20N4O2S

  • Molecular Weight

    464.54

  • SMILES

    C(C(NC1=NC=CS1)=O)(N2C(=O)C=3C(C2)=CC=C(C3)C=4C=C5C(=CC4)NC=C5)C6=CC=CC=C6

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound