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Molfinity

JC-171 - CAS 2112809-98-8

JC-171 - CAS 2112809-98-8

MF-0015820-01

$309.74 USD
$309.74 USD
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Product Details

  • Bioactivity

    JC-171, a selective inhibitor of the NLRP3 inflammasome, effectively inhibits LPS/ATP-induced interleukin-1β (IL-1β) release from J774A.1 macrophages with an IC50 of 8.45 μM[1].

  • Target

    NOD-like Receptor (NLR), Others

  • Related Pathways

    Immunology/Inflammation, Others

  • CAS Number

    2112703

  • Molecular Formula

    C16H17ClN2O5S

  • Molecular Weight

    384.83

  • SMILES

    COc1ccc(Cl)cc1C(=O)NCCc1ccc(cc1)S(=O)(=O)NO

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound