Molfinity

JCN037 - CAS 2305154-31-6

SKU:MF-0093324-01

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Size 5 mg 1 mL - 10 mM (in DMSO) 10 mg 25 mg 50 mg 100 mg

Product Details

Bioactivity
JCN037 is potent, non-covalent and brain-penetrant inhibitor of EGFR (EGFR, p-wtEGFR and pEGFRvIII with IC50 of 2.49 nM, 3.95 nM, 4.48 nM , respectively) .
Target
EGFR
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis, JAK/STAT signaling
CAS Number
2305117
Purity
>99.99%
Molecular Formula
C16H11BrFN3O2
Molecular Weight
376.18
SMILES
Fc1c(Br)cccc1Nc1ncnc2cc3OCCOc3cc12
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound