JE-133 - CAS 2579171-69-8

JE-133, an optically active isochromane-2H-chromene conjugate, displays both antioxidant and anti-inflammatory properties. As a neuroprotective agent, it effectively counters neuronal oxidative damage through modulation of the PI3K/Akt and MAPK signaling pathways. Additionally, JE-133 can suppress lipopolysaccharide (LPS) -induced neuroinflammation by influencing the JAK/STAT and Nrf2 signaling pathways [1] [2].

Akt, p38 MAPK, PI3K

MAPK, Cytoskeletal Signaling, PI3K/Akt/mTOR signaling

2579171-69-8

C23H24O7

412.43

C(OCC)(=O)[C@@H]1C(=CC=2C(O1)=CC=C(OC)C2)[C@H]3C=4C(C[C@@H](C)O3)=CC(O)=C(O)C4

-20°C

Ice Packs

Small Compound