JG26 - CAS 1464910-32-4

JG26 is a potent inhibitor of ADAM17, which can inhibit ADAM8, ADAM17, ADAM10 and MMP-12, with IC50 values of 12 nM, 1.9 nM, 150 nM and 9.4 nM, respectively, and can be used to study the immune system of the body.

SARS-CoV, Angiotensin-converting Enzyme (ACE), EGFR, Immunology/Inflammation related, ERK, MMP

Tyrosine Kinase/Adaptors, Microbiology/Virology, MAPK, Immunology/Inflammation, JAK/STAT signaling, Angiogenesis, Metabolism, Proteases/Proteasome

1464874

>99.99%

C19H22Br2N4O6S

594.27

S(N[C@H](CCCNC(N)=O)C(NO)=O)(=O)(=O)C1=CC=C(OCC2=CC(Br)=CC(Br)=C2)C=C1

-20°C

Ice Packs

Small Compound