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JH-II-127 - CAS 1700693-08-8

JH-II-127 - CAS 1700693-08-8

MF-0014250-01

$38.41 USD
$38.41 USD
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Product Details

  • Bioactivity

    JH-II-127 is an oral inhibitor of leucine-rich repeat kinase 2 (LRRK2), targeting WT LRRK2, G2019S LRRK2, and A2016T LRRK2 with IC50 values of 6.6 nM, 2.2 nM, and 47.7 nM, respectively.

  • Target

    LRRK2

  • Related Pathways

    Autophagy

  • CAS Number

    1700693-08-8

  • Purity

    0.9832

  • Molecular Formula

    C19H21ClN6O3

  • Molecular Weight

    416.86

  • SMILES

    CNc1nc(Nc2ccc(cc2OC)C(=O)N2CCOCC2)nc2[nH]cc(Cl)c12

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound