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Molfinity

JH-VIII-157-02 - CAS 1639422-97-1

JH-VIII-157-02 - CAS 1639422-97-1

MF-0033079-01

$120.88 USD
$120.88 USD
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Product Details

  • Bioactivity

    JH-VIII-157-02 is an inhibitor of ALK and inhibits echinoderm microtubule-associated protein-like 4-ALK (EML4-ALK) with IC50s of 2 nM for EML4-ALK G1202R, EML4-ALKwt, EML4-ALK C1156Y, EML4-ALK F1174L, and EML4-ALK F1174L.

  • Target

    ALK, Microtubule Associated

  • Related Pathways

    Cytoskeletal Signaling, Tyrosine Kinase/Adaptors, Angiogenesis

  • CAS Number

    1639324

  • Purity

    0.9958

  • Molecular Formula

    C28H27N5O2

  • Molecular Weight

    465.55

  • SMILES

    CCc1cc2C(=O)c3c([nH]c4cc(ccc34)C#N)C(C)(C)c2cc1-c1cnn(CC(=O)N(C)C)c1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound