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JH-XIV-68-3 - CAS 2426628-52-4
JH-XIV-68-3 - CAS 2426628-52-4
SKU:MF-0020741-01
Regular price
$1,927.85 USD
Regular price
$1,391.00 USD
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$1,927.85 USD
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Product Details
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Bioactivity
JH-XIV-68-3 is a selective inhibitor of the DYRK1A/B macrocycle, acting specifically on DYRK1A and DYRK1B in biochemical and cellular assays, and exhibiting antitumor effects in head and neck squamous cell carcinoma (HNSCC) cell lines.
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Target
DYRK, Others
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Related Pathways
Cell Cycle/Checkpoint, Others, Tyrosine Kinase/Adaptors
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CAS Number
2426628-52-4
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Molecular Formula
C21H17F3N8O
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Molecular Weight
454.41
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SMILES
C(#N)C1=C2C(=NN1C)N(C)C(=O)CCCN3C=C(C=4C5=CC2=CN=C5NC4)C(C(F)(F)F)=N3
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound