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Molfinity

JH-XIV-68-3 - CAS 2426628-52-4

JH-XIV-68-3 - CAS 2426628-52-4

SKU:MF-0020741-01

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  • Bioactivity

    JH-XIV-68-3 is a selective inhibitor of the DYRK1A/B macrocycle, acting specifically on DYRK1A and DYRK1B in biochemical and cellular assays, and exhibiting antitumor effects in head and neck squamous cell carcinoma (HNSCC) cell lines.

  • Target

    DYRK, Others

  • Related Pathways

    Cell Cycle/Checkpoint, Others, Tyrosine Kinase/Adaptors

  • CAS Number

    2426628-52-4

  • Molecular Formula

    C21H17F3N8O

  • Molecular Weight

    454.41

  • SMILES

    C(#N)C1=C2C(=NN1C)N(C)C(=O)CCCN3C=C(C=4C5=CC2=CN=C5NC4)C(C(F)(F)F)=N3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound