JHDM-IN-1 - CAS 1310809-17-6

JHDM-IN-1 (Compound 1), a Jumonji C domain-containing HDMs (JHDM) inhibitor, exhibits IC50s of 3.4 μM against JMJD2C, 4.3 μM against JMJD2A, 5.9 μM against JMJD2E, 10 μM against PHF8, and 43 μM against JMJD3, showcasing its inhibitory effectiveness across a spectrum of JHDM enzymes [1].

Others, Histone Demethylase

Others, Chromatin/Epigenetic

1310786

C27H29N3O6

491.54

N(C(OCC1=CC=C(CNCCCCN(C(/C=C/C(O)=O)=O)O)C=C1)=O)C=2C3=C(C=CC2)C=CC=C3

-20°C

Ice Packs

Small Compound