JHU-083 - CAS 1998725-11-3

JHU-083 is an orally available, blood-brain barrier-crossing, selective glutaminase antagonist that improves cognitive performance and normalizes abnormal hippocampal glutaminase activity in APOE4 mice.

Glutaminase, RAAS

Proteases/Proteasome, Endocrinology/Hormones

1998711

0.9953

C14H24N4O4

312.37

[C@H](NC([C@H](CC(C)C)N)=O)(CCC(C=[N+]=[N-])=O)C(OCC)=O

-20°C

Ice Packs

Small Compound