JHU-58 - CAS 1632140-61-4

JHU-58 is a novel dipeptide MrgC agonist. JHU-58 inhibited both mechanical and heat hypersensitivity in rats after an L5 spinal nerve ligation (SNL) . JHU58 attenuated the evoked excitatory postsynaptic currents in substantia gelatinosa (SG) neurons in wild-type mice, but not in Mrg knockout mice, after peripheral nerve injury.

Others

Others

1632075

C19H24N6O2

368.43

C([C@H](C(N[C@@H](CC1=CC=CC=C1)C(N)=O)=O)N)C2=CC=C(NC(=N)N)C=C2

-20°C

Ice Packs

Small Compound