JIP-1 (153-163) - CAS 438567-88-5

JIP-1 (153-163) is a peptide inhibitor of c-Jun N-terminal kinase (JNK), based on residues 153-163 of JNK-interacting protein-1 (JIP-1) . JIP-1 (153-163) binds to JNK with affinity in the micromolar range and minimally inhibits p38 and ERK.

JNK

MAPK

438567-88-5

C61H104N20O14

1341.6

C([C@@H](NC([C@@H](NC(=O)[C@H]1N(C([C@H](CCCNC(=N)N)N)=O)CCC1)CCCCN)=O)CCCNC(=N)N)(=O)N2[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CC=CC=C3)C(N)=O)=O)CC(C)C)=O)CC(N)=O)=O)CC(C)C)=O)[C@@H](C)O)=O)[C@@H](C)O)=O)CCC2

-20°C

Ice Packs

Peptide