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Molfinity

JK-P3 - CAS 942655-44-9

JK-P3 - CAS 942655-44-9

MF-0013621-01

$31.68 USD
$31.68 USD
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Product Details

  • Bioactivity

    JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 μM) . JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays. The compound blocks wound healing and tube formation in HUVEC without effecting endothelial cell proliferation.

  • Target

    FGFR, VEGFR

  • Related Pathways

    Tyrosine Kinase/Adaptors, Angiogenesis

  • CAS Number

    942602

  • Purity

    >99.99%

  • Molecular Formula

    C18H17N3O3

  • Molecular Weight

    323.35

  • SMILES

    COc1ccc(cc1OC)C(=O)Nc1cc([nH]n1)-c1ccccc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound