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JMV6944 - CAS 2871774-93-3
JMV6944 - CAS 2871774-93-3
SKU:MF-0148348-01
Regular price
$1,383.80 USD
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$1,383.80 USD
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Product Details
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Bioactivity
JMV6944 is a PXR agonist that competitively inhibits the binding of ligands to the ligand-binding domain (LBD) of human PXR, with an IC50 value of 680 nM. Additionally, JMV6944 induces the expression of CYP3A4 mRNA in cultures of freshly isolated primary human hepatocytes.
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CAS Number
2871774-93-3
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Molecular Formula
C30H38N4O2S
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Molecular Weight
518.71
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SMILES
O=S(=O)(NC=1C=CC2=C(N=C(N2CC=3C=CC=CC3)CCCCCCCN)C1)C=4C(=CC(=CC4C)C)C
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound