JMX0207 - CAS 33580-97-1

JMX0207 is a niclosamide-derived compound that demonstrates enhanced inhibitory efficacy against the NS3–NS2B protein-protein interaction essential for viral protease activity.JMX0207 effectively suppresses viral replication and protease function, showing superior antiviral activity in cell-based assays and significantly reducing Zika virus infection levels in three-dimensional mini-brain organoid models derived from pluripotent neural stem cells, thus highlighting its promise as an optimized antiviral lead compound.

Others

Others

33482

C13H8ClN3O6

337.67

O=C(C1=CC=CC([N+]([O-])=O)=C1O)NC2=CC=C([N+]([O-])=O)C=C2Cl

-20°C

Ice Packs

Small Compound