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Molfinity

JNc-440 - CAS 1119503-63-7

JNc-440 - CAS 1119503-63-7

MF-0036540-01

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Product Details

  • Bioactivity

    JNc-440 is a potent anti-hypertensive agent. jNc-440 enhances the interaction between the transient receptor potential vanilloid subtype 4 (TRPV4) and calcium-activated potassium channel 3 (KCa2.3) in endothelial cells. jNc-440 also increases vasodilation and has hypotensive activity in mice.

  • Target

    Others, TRP/TRPV Channel, Potassium Channel

  • Related Pathways

    Membrane transporter/Ion channel, Others

  • CAS Number

    1119503-63-7

  • Molecular Formula

    C26H24N4O3

  • Molecular Weight

    440.49

  • SMILES

    O=C(NCCCNC(=O)c1nc2ccccc2c(=O)[nH]1)C(c1ccccc1)c1ccccc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound