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Molfinity

JNJ-10198409 - CAS 627518-40-5

JNJ-10198409 - CAS 627518-40-5

MF-0018652-01

$31.68 USD
$31.68 USD
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Product Details

  • Bioactivity

    JNJ- 10198409 is a relatively selective and ATP competitive PDGF-RTK inhibitor (IC50=2 nM) . JNJ-10198409 has good activity against PDGFR-β kinase (IC50=4.2 nM) and PDGFR-α kinase (IC50=45 nM) . It is a dual-mechanism, antiangiogenic, and tumor cell antiproliferative agent.

  • Target

    PDGFR

  • Related Pathways

    Angiogenesis, Tyrosine Kinase/Adaptors

  • CAS Number

    627473

  • Purity

    0.9851

  • Molecular Formula

    C18H16FN3O2

  • Molecular Weight

    325.34

  • SMILES

    COc1cc2Cc3c(Nc4cccc(F)c4)n[nH]c3-c2cc1OC

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound