JNJ-10311795 - CAS 518062-14-1

JNJ-10311795 (RWJ-355871) is a potent dual inhibitor of neutrophil elastase (Ki = 38 nM) and mast cell chymase (Ki = 2.3 nM) with significant anti-inflammatory activity, useful for studying pneumonia.

Cysteine Protease

Proteases/Proteasome

518047

0.9919

C40H35N2O6P

670.69

O=C(C=1C=CC=2C=CC=CC2C1)N3CCC(N(C(=O)C4=CC=5C=CC=CC5C=C4C(=O)C(C6=CC=CC=7C=CC=CC76)P(=O)(O)O)C)CC3

-20°C

Ice Packs

Small Compound