Molfinity

JNJ-28583113 - CAS 2765255-93-2

SKU:MF-0095366-01

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Product Details

Bioactivity
JNJ-28583113 is a brain-penetrant TRPM2 antagonist that induces phosphorylation of GSK3α and β subunits, protecting cells from oxidative stress-induced cell death. It inhibits microglia response to pro-inflammatory stimuli, used in the study of neurological diseases.
Target
TRP/TRPV Channel
Related Pathways
Membrane transporter/Ion channel
CAS Number
2765160
Purity
0.9857
Molecular Formula
C19H21F3N2O2
Molecular Weight
366.38
SMILES
O=C(OCC)CN1N=C(C=2C=CC(=CC2)C(F)(F)F)C3=C1CCCCC3
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound