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Molfinity

JNJ-38158471 - CAS 951151-97-6

JNJ-38158471 - CAS 951151-97-6

SKU:MF-0017083-01

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  • Bioactivity

    JNJ-38158471 (CS-2660), a highly selective, orally available, well tolerated VEGFR2 inhibitor with IC50 of 40 nM, inhibits closely related tyrosine kinases such as Ret and Kit with IC50 of 180 nM and 500 nM.

  • Target

    C-RET, VEGFR, c-Kit

  • Related Pathways

    Angiogenesis, Tyrosine Kinase/Adaptors, Apoptosis

  • CAS Number

    951048

  • Purity

    0.9804

  • Molecular Formula

    C15H17ClN6O3

  • Molecular Weight

    364.79

  • SMILES

    CCNC(=O)Nc1ccc(Oc2ncnc(N)c2\C=N\OC)cc1Cl

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound