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JNJ-39758979 - CAS 1046447-90-8

JNJ-39758979 - CAS 1046447-90-8

MF-0018789-01

$40.65 USD
$40.65 USD
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Product Details

  • Bioactivity

    JNJ-39758979 is a selective and high-affinity histamine H4 receptor antagonist (Kis: 12.5, 5.3, and 25 nM for human, mouse, and monkey histamine H4 receptor, respectively) . JNJ-39758979 functionally antagonizes histamine-induced cAMP inhibition with a pA2 of 7.9 in transfected cells.

  • Target

    Histamine Receptor

  • Related Pathways

    Immunology/Inflammation, Neuroscience, GPCR/G Protein

  • CAS Number

    1046349

  • Purity

    0.9962

  • Molecular Formula

    C11H19N5

  • Molecular Weight

    221.3

  • SMILES

    CC(C)c1cc(nc(N)n1)N1CC[C@@H](N)C1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound