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Molfinity

JNJ-46281222 - CAS 1254980-38-5

JNJ-46281222 - CAS 1254980-38-5

SKU:MF-0033082-01

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  • Bioactivity

    JNJ-46281222 is a metabotropic glutamate (mGlu) 2-selective, highly potent positive allosteric modulator (PAM) with nanomolar affinity (Kd = 1.7 nM) and high modulatory potency (pEC50 = 7.71) .

  • Target

    GluR

  • Related Pathways

    Neuroscience

  • CAS Number

    1254937

  • Molecular Formula

    C23H25F3N4

  • Molecular Weight

    414.47

  • SMILES

    FC(F)(F)c1c(CN2CCC(CC2)c2ccccc2)ccn2c(CC3CC3)nnc12

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound