Molfinity

JNJ-54175446 - CAS 1627902-21-9

SKU:MF-0033084-01

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Product Details

Bioactivity
JNJ-54175446 (JNJ-5446) is a CNS-permeable and selective P2X7 receptor antagonist that attenuates the release of IL-1β/IL-18 from microglia, and may be used in the study of depression.
Target
P2X Receptor
Related Pathways
Neuroscience, Membrane transporter/Ion channel
CAS Number
1627872
Purity
>99.99%
Molecular Formula
C18H13ClF4N6O
Molecular Weight
440.78
SMILES
C[C@H]1N(CCc2c1nnn2-c1ncc(F)cn1)C(=O)c1cccc(c1Cl)C(F)(F)F
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound