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JNJ-63576253 free base - CAS 2110426-27-0

JNJ-63576253 free base - CAS 2110426-27-0

MF-0093824-01

$35.41 USD
$35.41 USD
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Product Details

  • Bioactivity

    JNJ-63576253 free base (TRC253) is a potent and orally active full antagonist of androgen receptor (AR), with IC50s of 37 and 54 nM for F877L mutant AR and wild-type AR in LNCaP cells. JNJ-63576253 can be used for the research of castration-resistant prostate cancer (CRPC) .

  • Target

    Androgen Receptor

  • Related Pathways

    Endocrinology/Hormones

  • CAS Number

    2110399

  • Purity

    0.9832

  • Molecular Formula

    C23H21F3N6O2S

  • Molecular Weight

    502.51

  • SMILES

    FC(F)(F)c1cc(cnc1C#N)N1C(=S)N(c2ccc(OC3CCNCC3)nc2)C2(CCC2)C1=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound