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Molfinity

JNK-IN-8 - CAS 1410880-22-6

JNK-IN-8 - CAS 1410880-22-6

SKU:MF-0019499-01

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  • Bioactivity

    JNK-IN-8 (JNK Inhibitor XVI) is an irreversible JNK1/2/4 inhibitor (IC50: 4.7/18.7/1 nM) with over 10-fold selectivity compared to MNK2 and Fms, and no inhibition of Met, c-Kit, or PDGFRβ in the A375 cell line.

  • Target

    JNK, c-Kit

  • Related Pathways

    Tyrosine Kinase/Adaptors, MAPK

  • CAS Number

    1410852

  • Purity

    >99.99%

  • Molecular Formula

    C29H29N7O2

  • Molecular Weight

    507.59

  • SMILES

    CN(C)CC=CC(=O)Nc1cccc(c1)C(=O)Nc1ccc(Nc2nccc(n2)-c2cccnc2)c(C)c1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound