JO146 - CAS 130727-21-8

JO146 is a protease inhibitor for Chlamydia trachomatis high temperature requirement A (CtHtrA) and human neutrophil elastase (HNE), with IC50 values of 21.86 μM for CtHtrA and 1.15 μM for HNE, respectively. It is effective in inhibiting bacterial infections.

Serine Protease, Others

Others, Proteases/Proteasome

130698

C31H44N3O7P

601.67

P(C(NC(=O)[C@H]1N(C([C@@H](NC(OC(C)(C)C)=O)[C@H](C)C)=O)CCC1)C(C)C)(OC2=CC=CC=C2)(OC3=CC=CC=C3)=O

-20°C

Ice Packs

Small Compound