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Molfinity

JPHM-2-167 - CAS 1258877-17-6

JPHM-2-167 - CAS 1258877-17-6

MF-0113683-01

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Product Details

  • Bioactivity

    PHM-2-167 (Compound 11) is a selective inhibitor of the prolyl hydroxylase domain enzyme (PHD) . It inhibits PHD2 and PHD3 with IC50 values of 0.253 μM and 3.95 μM, respectively. PHM-2-167 is applicable for research in chronic kidney disease.

  • Target

    HIF/HIF Prolyl-Hydroxylase

  • Related Pathways

    Chromatin/Epigenetic, Metabolism

  • CAS Number

    1258854

  • Molecular Formula

    C30H28N6O2

  • Molecular Weight

    504.582

  • SMILES

    O=C1N(C=2C=CC(=CC2)C=3C=CC=CC3)C(=O)C4(N1C5=NC=CC=N5)CCN(CC6=NC=CC=C6C)CC4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound