JQ-1 (carboxylic acid) - CAS 202592-23-2

JQ-1 (carboxylic acid) is a cell-permeable BRD4 inhibitor with IC50s of 77 nM for BRD4 (1) and 33 nM for BRD4 (2)

PD-1/PD-L1, Epigenetic Reader Domain

Apoptosis, Immunology/Inflammation, Cell Cycle/Checkpoint, Chromatin/Epigenetic

202567

0.999

C19H17ClN4O2S

400.88

CC=1C2=C(N3C([C@H](CC(O)=O)N=C2C4=CC=C(Cl)C=C4)=NN=C3C)SC1C

-20°C

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