Molfinity

JR-AB2-011 - CAS 2411853-34-2

SKU:MF-0022675-01

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Size 1 mg 5 mg 1 mL - 10 mM (in DMSO) 10 mg 25 mg 50 mg 100 mg

Product Details

Bioactivity
JR-AB2-011 is a selective mTORC2 inhibitor with an IC50 value of 0.36 μM. It inhibits mTORC2 activity by blocking Rictor-mTOR association (Ki: 0.19 μM) and exhibits cytotoxicity in glioblastoma [1].
Target
MTOR
Related Pathways
PI3K/Akt/mTOR signaling
CAS Number
2411817
Purity
0.9941
Molecular Formula
C17H14Cl2FN3OS
Molecular Weight
398.28
SMILES
CC1CN(C(=O)Nc2ccc(Cl)c(Cl)c2)\C(S1)=N\c1ccc(F)cc1
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound