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JRD-SIK1/2i-4 - CAS 2810810-00-3
JRD-SIK1/2i-4 - CAS 2810810-00-3
SKU:MF-0112694-01
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Product Details
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Bioactivity
JRD-SIK1/2i-4 is a SIK1/2 inhibitor that induces nuclear translocation of CRTC3 at low micromolar concentrations. It is expected to saturate SIK1 and SIK2, but not SIK3.
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Target
Interleukin, SIK, TNF
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Related Pathways
Apoptosis, PI3K/Akt/mTOR signaling, Immunology/Inflammation
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CAS Number
2810810-00-3
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Molecular Formula
C21H20N6O2
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Molecular Weight
388.42
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SMILES
N#CC=1N=CC(OC2CN(C)C2)=C(C1)C=3C=CN4N=C(C=C4C3)NC(=O)C5CC5
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound