JTK-853 - CAS 954389-09-4

JTK-853 is a novel, non-nucleoside inhibitor of Hepatitis C Virus (HCV) polymerase, exhibiting effective antiviral activity in HCV replicon cells with EC50s of 0.38 μM for genotype 1a H77 strain and 0.035 μM for genotype 1b Con1 strain.

Others, HCV Protease

Others, Microbiology/Virology, Proteases/Proteasome

954389-09-4

C28H23F7N6O4S2

704.64

C(NCC1=CC(F)=C(OC(F)(F)F)C=C1)(=O)[C@@H]2N(S(=O)(=O)C3=CC=C(C(F)(F)F)C=C3)CCN(C2)C4=NC=5C(S4)=CN=C(N5)C6CC6

-20°C

Ice Packs

Small Compound